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KMID : 0438420140210020155
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Korean Journal of Bone Metabolism
2014 Volume.21 No. 2 p.155 ~ p.159
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Atypical Femoral Fracture Combined with Osteonecrosis of Jaw During Osteoporosis Treatment with Bisphosphonate
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Won Youg-Un
Lim Joon-Ryul
Kim Young-Hwan
Song Hyung-Keun
Yang Kyu-Hyun
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Abstract
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Bisphosphonate, a potent anti-resorptive agent, is generally accepted as a safe, effective, well tolerated treatment for postmenopausal osteoporosis. Atypical femoral fracture (AFF) and bisphosphonate related osteonecrosis of jaw (BRONJ) are the increasing morbidities in patients treated with long term bisphosphonate. Pathogenic mechanisms of AFF and BRONJ are not fully identified and not identical. We report a case of BRONJ followed by AFF and its nonunion in a 67-year-old woman patient receiving an oral bisphosphonate during 7 years for the treatment of osteoporosis.
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KEYWORD
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Atypical femoral fracture, Bisphosphonate
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